Helmholtz-Zentrum Geesthacht, 2018-04-24
http://www.hzg.de/052787/index_0052787.html.en

HVI Publications

Selected Publications

  • S. Staufenbiel, M. Merino, W. Li, M.-D. Huang, S. Baudis, A. Lendlein, R. H. Müller, C. Wischke, Surface characterization and protein interaction of a series of model poly[acrylonitrile-co-(N-vinyl pyrrolidone)] nanocarriers for drug targeting, Int. J. Pharm., 2015, 485, 87-96.
  • T. Bhuvanesh Vijaya Bhaskar, T. Roch, O. Romero, N. Ma, K. Kratz, A. Lendlein, Single and competitive protein adsorption on polymeric surfaces, Polym. Adv. Technol., 2015, 26, 1387-1393.
  • M. C. Lukowiak, S. Wettmarshausen, G. Hidde, P. Landsberger, V. Boenke, K. Rodenacker, U. Braun, J. F. Friedrich, A. Gorbushina, and R. Haag, Polyglycerol coated polypropylene surfaces for protein and bacteria resistance, Polymer Chemistry, 2015, 6, 1350-1359.
  • T. Becherer, S. Heinen, Q. Wei, R. Haag, M. Weinhart, In-depth analysis of switchable glycerol based polymeric coatings for cell sheet engineering, Acta Biomater. 2015, 25 43–55.
  • S. Yu, X. Xu, C. Yigit, M. van der Giet, W. Zidek, J. Jankowski, J. Dzubiella, M. Ballauff, Interaction of human serum albumin with short polyelectrolytes: a study by calorimetry and computer simulations, Soft Matter, 2015, 11, 4630-4639.
  • Q. Wei, T. Becherer, S. Angioletti-Uberti, J. Dzubiella, C. Wischke, A. T. Neffe, A. Lendlein, M. Ballauff, R. Haag, Protein interactions with polymer coatings and biomaterials, Angew Chem Int Edit, 2014, 53, 8004-8031.
  • A. T. Neffe, M. von Ruesten-Lange, S. Braune, K. Lützow, T. Roch, K. Richau, A. Krüger, T. Becherer, A. F. Thünemann, F. Jung, R. Haag, A. Lendlein, Multivalent grafting of hyperbranched oligo- and polyglycerols shielding rough membranes to mediate hemocompatibility, J Mater Chem B, 2014, 2, 3626-3635.
  • A. Boreham, M. Pfaff, E. Fleige, R. Haag, U. Alexiev, Nanodynamics of dendritic core-multishell nanocarriers, Langmuir, 2014, 30 (6), 1686-1695.
  • Q. Wei, T. Becherer, P. Ludwig M. Noeske, I. Grunwald, R. Haag, A universal approach to crosslinked hierarchical polymer multilayers as stable and highly effective antifouling coatings, Adv Mater, 2014, 26 (17), 2688-2693.
  • D. Steinhilber, T. Rossow, S. Wedepohl, F. Paulus, S. Seiffert, and R. Haag, A microgel construction kit for bioorthogonal encapsulation and pH-controlled release of living cells, Angew Chem Int Edit, 2013, 52, 13538–13543; Ein Mikrogelbaukasten für die bioorthogonale Verkapselung und pH-gesteuerte Freisetzung von lebenden Zellen, Angew Chem, 2013, 125, 13780–13785.
  • M. Sarem, F. Moztarzadeh, M. Mozafari, V. P. Shastri, Optimization strategies on the structural modeling of gelatin/chitosan scaffolds to mimic human meniscus tissue, Mater Sci Eng C, 2013, 33 (8), 4777-4785.
  • K. Krueger, C. Terne,C. Werner, U. Freudenberg, V. Jankowski, W. Zidek, J. Jankowski, Characterization of polymer membranes by MALDI mass spectrometric imaging techniques, Anal Chem, 2013, 85 (10), 4998−5004.
  • S. Heilmann, S. Küchler, C. Wischke, A. Lendlein, C. Stein, M. Schäfer-Korting, A thermosensitive morphine-containing hydrogel for the treatment of large-scale skin wounds, Int J Pharm, 2013, 444 (1–2), 96-102.
  • M. Lange, S. Braune, K. Luetzow, K. Richau, N. Scharnagl, M. Weinhart, A. T. Neffe, F. Jung, R. Haag, A. Lendlein, Surface functionalization of poly(ether imide) membranes with linear, methylated oligoglycerols for reducing thrombogenicity, Macromol Rapid Commun 2012, 33 (17), 1487–1492.
  • N. Welsch, J. Dzubiella, A. Graebert, and M. Ballauff, Protein binding to soft polymeric surfaces: a quantitative study by fluorescence spectroscopy, Soft Matter, 2012, 8, 12043.

All Publications

Publications 2015

  • S. Seiffert, F. Friess, A. Lendlein, C. Wischke, Faster Droplet Production by Delayed Surfactant-Addition in Two-Phase Microfluidic to form thermos-sensitive Microgels, J. Colloid. Interf. Sci., 2015, 452, 38-42.
  • S. Staufenbiel, M. Merino, W. Li, M.-D. Huang, S. Baudis, A. Lendlein, R. H. Müller, C. Wischke, Surface characterization and protein interaction of a series of model poly[acrylonitrile-co-(N-vinyl pyrrolidone)] nanocarriers for drug targeting, Int. J. Pharm., 2015, 485, 87-96.
  • T. Bhuvanesh Vijaya Bhaskar, T. Roch, O. Romero, N. Ma, K. Kratz, A. Lendlein, Single and competitive protein adsorption on polymeric surfaces, Polym. Adv. Technol., 2015, 26, 1387-1393.
  • T. B. Vijaya Bhaskar, N. Ma, A. Lendlein, T. Roch, The interaction of human macrophage subsets with silicone as a biomaterial, Clin. Hemorheol. Microcirc., 2015, 61, 119-133.
  • T. Roch, K. Kratz, N. Ma, A. Lendlein, Polymeric inserts differing in their chemical composition as substrates for dendritic cell cultivation, Clin. Hemorheol. Microcirc., 2015, 61, 347-357.
  • J. Görs, T. Roch, L. Tartivel, M. Behl, N. Ma, A. Lendlein, Immuno-compatibility of amphiphilic ABA triblock copolymer based hydrogel films for biomedical applications, Polym Adv. Technol., 2015, 26, 1378-1386.
  • T. Roch, K. K. Julich-Gruner, A. T. Neffe, N. Ma, A. Lendlein, Immuno-compatibility of desaminotyrosine and desaminotyrosyl tyrosine functionalized star-shaped oligo(ethylene glycol)s with different molecular weights, Mater. Res. Soc. Symp. Proc., 2015, 1718, 97-102.
  • W. Wang, K. Kratz, M. Behl, W. Yan, Y. Liu, X. Xu, S. Baudis, Z. Li, A. Kurtz, A. Lendlein, N. Ma, The interaction of adipose-derived human mesenchymal stem cells and polyether ether ketone, Clin. Hemorheol. Microcirc., 2015, 61, 301-321.
  • T. Roch, N. Ma, K. Kratz, A. Lendlein, Cell-based detection of microbial biomaterial contaminations, Clin. Hemorheol. Microcirc., 2015, 60. 51-63.
  • C. Stein, Opioid receptors, Annu. Rev. Med., 2015, 67:5.1-5.19 [E-Pub ahead of print]. DOI: 10.1146/annurev-med-062613-093100
  • M. C. Lukowiak, S. Wettmarshausen, G. Hidde, P. Landsberger, V. Boenke, K. Rodenacker, U. Braun, J. F. Friedrich, A. Gorbushina, and R. Haag, Polyglycerol coated polypropylene surfaces for protein and bacteria resistance, Polymer Chemistry, 2015, 6, 1350-1359.
  • T. Becherer, C. Grunewald, V. Engelschalt, G. Multhaup, T. Risse, and R. Haag, Polyglycerol Based Coatings to Reduce Nonspecific Protein Adsorption in Sample Vials and on SPR Sensors, Anal. Chim. Acta, 2015, 867, 47-55.
  • C. Holzhausen, D. Gröger, L. Mundhenk, C. K. Donat, J. Schnorr, R. Haag, and A. D. Gruber, Biodistribution, cellular localization, and in vivo tolerability of 35S-labeled antiinflammatory dendritic polyglycerol sulfate amine, J. Nanopart. Res., 2015, 17, 116.
  • T. Becherer, M. Vieira Nascimento, J. Sindram, P.-L. M. Noeske, Q. Wei, R. Haag, and I. Grunwald, Fast and Easily Applicable Glycerol Based Nonfouling Spray-coatin, Prog. Org. Coat., 2015, 87, 146–154.
  • M. Jäger, T. Becherer, J. Bruns, and R. Haag, Antifouling Coatings on SOI Microring Resonators for Bio Sensing Applications, Sensors & Actuators: B. Chemical 2015, 223, 400-405.
  • Q. Wei and R. Haag, Universal Polymer Coatings and Their Representative Biomedical Applications, Mater. Horiz., 2015, 2, 567-577.
  • T. Becherer, S. Heinen, Q. Wei, R. Haag, M. Weinhart, In-depth analysis of switchable glycerol based polymeric coatings for cell sheet engineering, Acta Biomater. 2015, 25 43–55.
  • F. Di Lorenzo, J. Hellwig, R. von Klitzing, and S. Seiffert, Macroscopic and Microscopic Elasticity of Heterogeneous Polymer Gels, ACS Macro Lett., 2015, 4, 698–703.
  • J. Bergueiro, M. Calderon, Thermoresponsive Nanodevices in Biomedical Applications, Macromol Biosci, 2015, 15 (2), 183-199.
  • C. Yigit, J. Heyda, M. Ballauff, J. Dzubiella, Like-charged protein-polyelectrolyte complexation driven by charge patches, J. Chem. Phys. , 2015, 143, 064905.
  • S. Yu, X. Xu, C. Yigit, M. van der Giet, W. Zidek, J. Jankowski, J. Dzubiella, M. Ballauff, Interaction of human serum albumin with short polyelectrolytes: a study by calorimetry and computer simulations, Soft Matter, 2015, 11, 4630-4639.
  • M. Oberle, C. Yigit, S. Angioletti-Uberti, J. Dzubiella, M. Ballauff, Competitive Protein Adsorption to Soft Polymeric Layers: Binary Mixtures and Comparison to Theory, J. Phys. Chem. B, 2015, 119, 3250-3258.
  • F. Böhringer, V. Jankowski, P.R. Gaijala, W. Zidek, J. Jankowski, Release of uremic retention solutes from protein binding by hypertonic predilution hemodiafiltration, Asaio J., 2015, 61 (1), 55-60.
  • A. Ostrowski, D. Nordmeyer, A. Boreham, C. Holzhausen, L. Mundhenk, C. Graf, M. C. Meinke, A. Vogt, S. Hadam, J. Lademann, E. Rühl, U. Alexiev, A. D. Gruber, Overview about the localization of nanoparticles in tissue and cellular context by different imaging techniques, Beilstein Journal of Nanotechnology, 2015, 6, 263-280.

Publications 2014

  • A. T. Neffe, M. von Ruesten-Lange, S. Braune, K. Lützow, T. Roch, K. Richau, A. Krüger, T. Becherer, A. F. Thünemann, F. Jung, R. Haag, A. Lendlein, Multivalent grafting of hyperbranched oligo- and polyglycerols shielding rough membranes to mediate hemocompatibility, J Mater Chem B, 2014, 2, 3626-3635.
  • T. Roch, O. Akymenko, A. Krüger, F. Jung, N. Ma, A. Lendlein, Expression pattern analysis and activity determination of matrix metalloproteinase derived from human macrophage subsets, Clin. Hemorheol. Microcirc. 2014, 58, 1, 147-158.
  • A. Krüger, A. Mayer, T. Roch, C. Schulz, A. Lendlein, F. Jung, Angiogenically stimulated alternative monocytes maintain their pro-angiogenic and non-inflammatory phenotype in long-term co-cultures with HUVEC, Clin. Hemorheol. Microcirc. 2014, 58, 1, 229-240.
  • T. Roch, C. Schulz , F. Jung, N. Ma, A. Lendlein, Interaction of poly(ether imide) films with early immune mechanisms, Clin Hemorheol Micro, 2014, 57, 203-212.
  • C. Schulz , M. von Rüsten-Lange, A. Krüger, A. Lendlein, F. Jung, Adherence and shear-resistance of primary human endothelial cells on smooth poly(ether imide) films, Clin Hemorheol Micro, 2014, 57, 147-158.
  • S. M. S. Schönwälder, F. Bally, L. Heinke, C. Azucena, Ö. D. Bulut, S. Heißler, F. Kirschhöfer, T. P. Gebauer, A. T. Neffe, A. Lendlein, G. Brenner-Weiß, J. Lahann, A. Welle, J. Overhage, C. Wöll, Interaction of human plasma proteins with thin gelatinbased hydrogel films: a QCM-D and ToF-SIMS study, Biomacromolecules 2014, 15, 7, 2898-2406.
  • S. Ullm, A. Krüger, C. Tondera, T. P. Gebauer, A. T. Neffe, A. Lendlein, F. Jung, J. Pietzsch, Biocompatibility and Inflammatory Response in vitro and in vivo to Gelatinbased Biomaterials with Tailorable Elastic Properties, Biomaterials 2014, 35, 37, 9755- 9766.
  • N. Arya, T. P. Gebauer, A. T. Neffe, A. Lendlein, V. P. Shastri, Chondrocyte redifferentiation on ethyl lysine diisocyanate cross-linked gelatin based 3-D scaffolds: application in cartilage tissue engineering, J Tissue Eng Regen Med 2014, 8, s1, 253.
  • W. Wang, X. Xu, Z. Li, A. Lendlein, N. Ma, Genetic engineering of mesenchymal stem cells by non-viral gene delivery, Clin Hemorheol Microcirc 2014, 58, 1, 19-48.
  • X. Xu, W. Wang, K. Kratz, L. Fang, Z. Li, A. Kurtz, N. Ma, A. Lendlein, Controlling Major Cellular Processes of Human Mesenchymal Stem Cells Using Microwell Structures, Adv. Healthc Mater 2014, 3, 12, 1991-2003.
  • A. T. Neffe, H. D. Santan, S. Kamlage, B. Gottschalk, A. Lendlein, Micellization of Aminoterminated Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly-(ethylene glycol) in the Presence of Hyaluronic Acid, Macromol Symp 2014, 345, 1, 91-97.
  • M. A. Molina, M. Giulbudagian, M. Calderón, Positively Charged Thermoresponsive Nanogels for Anticancer Drug Delivery, Macromolecular Chemistry and Physics 2014, 215, 2414-2419.
  • M. Giulbudagian, M. Asadian-Birjand, D. Steinhilber, K. Achazi, M. A. Molina, M. Calderón, Fabrication of Thermoresponsive Nanogels by Thermo-Nanoprecipitation and in situ Encapsulation of Bioactives, Polymer Chemistry 2014, 5, 6909-6913.
  • F. Di Lorenzo, S. Seiffert, Tracer Diffusion in heterogeneous Polymer Networks, Macromol. Chem. Phys. 2014, 215, 2097–2111.
  • Q. Wei, T. Becherer, S. Angioletti-Uberti, J. Dzubiella, C. Wischke, A. T. Neffe, A. Lendlein, M. Ballauff, R. Haag, Protein interactions with polymer coatings and biomaterials, Angew Chem Int Edit, 2014, 53, 8004-8031.
  • Q. Wei, K. Achazi, H. Liebe, A. Schulz, P.-L. M. Noeske, I. Grunwald, R. Haag, Mussel-inspired dendritic polymers as universal multifunctional coatings, Angew. Chem. Int. Ed. 2014, 122, 684-692.
  • Q. Wei, C. Schlaich, S. Prévost, A. Schulz, C. Böttcher, M. Gradzielski, Z. Qi, R. Haag, C. A. Schalley, Supramolecular polymers as surface coatings: rapid fabrication of healable superhydrophobic and slippery surfaces, Adv. Mater. 2014 26, 7358–7364.
  • Q. Wei, T. Becherer, P.-L. M. Noeske, I. Grunwald, R. Haag, A universal approach to crosslinked hierarchical polymer multilayers as stable and highly effective antifouling coatings, Adv Mater, 2014, 26 (17), 2688-2693.
  • Q. Wei, S. Krysiak, K. Achazi, T. Becherer, P.-L. M. Noeske, F. Paulus, H. Liebe, I. Grunwald, J. Dernedde, A. Hartwig, T. Hugel, R. Haag, Multivalent anchored and crosslinked hyperbranched polyglycerol monolayers as antifouling coating for titanium oxide surfaces, Colloids Surf. B 2014, 122, 684-92.
  • Q. Wei, T. Becherer, R. Mutihac, P.-L. M. Noeske, F. Paulus, R. Haag, I. Grunwald, Multivalent Anchoring and Crosslinking of mussel-inspired antifouling surface coatings, Biomacromolecules, 2014, 15, 3061−3071.
  • C. A. Jagla, P. Martus, C. Stein, Peripheral opioid receptor blockade increases postoperative morphine demands - a randomized, double-blind, placebo-controlled trial, Pain 2014, 155, 2056–62.
  • N. Alnasif, C. Zoschke, E. Fleige, R. Brodwolf, A. Boreham, E. Rühl, K.-M. Eckl, H.-F. Merk, H. C. Hennies, U. Alexiev, R. Haag, S. Küchler, M. Schäfer-Korting, Penetration of normal, damaged and diseased skin - an in vitro study on dendritic core-multishell nanotransporters, J Control Release, 2014, 185, 45-50.
  • A. Boreham, R. Brodwolf, M. Pfaff, T.-Y. Kim, T. Schlieter, L. Mundhenk, A. D. Gruber, D. Gröger, K. Licha, R. Haag, U. Alexiev, Temperature and environment dependent dynamic properties of a dendritic polyglycerol sulfate, Polym. Adv. Technol. 2014, 25, 11, 1329–1336.
  • A. Boreham, M. Pfaff, E. Fleige, R. Haag, U. Alexiev, Nanodynamics of dendritic core-multishell nanocarriers, Langmuir, 2014, 30 (6), 1686-1695.
  • A. Ostrowski, D. Nordmeyer, A. Boreham, R. Brodwolf, L. Mundhenk, J. W. Fluhr, J. Lademann, C. Graf, E. Rühl, U. Alexiev, A. D. Gruber, Skin barrier disruptions in tape stripped and allergic dermatitis models have no effect on dermal penetration and systemic distribution of AHAPS-functionalized silica nanoparticles, Nanomed- Nanotechnol 2014, 10, 7, 1571-1581.
  • A. M. Schulz, C. Terne, V. Jankowski, G. Cohen, M. Schaefer, F. Boehringer, M. Tepel, D. Kunkel, W. Zidek, J. Jankowski, Modulation of NADPH oxidase activity by known uraemic retention solutes, Eur. J. Clin. Invest. 2014, 44, 8, 802-811.

Publications 2013

  • S. Braune, M. von Ruesten-Lange, C. Mrowietz, K. Lützow, T. Roch, A. T. Neffe, A. Lendlein, F. Jung, Dynamic in vitro hemocompatibility testing of poly(ether imide) membranes functionalized with linear, methylated oligoglycerol and oligo(ethylene glycol), Clin Hemorheol Micro, 2013, 54 (3), 235-248.
  • T. Roch, K. Kratz, N. Ma, F. Jung, A. Lendlein, The influence of polystyrene and poly(ether imide) inserts with different roughness, on the activation of dendritic cells, Clin Hemorheol Micro, 2013, 55, 157-168.
  • A. T. Neffe, T. Gebauer, A. Lendlein, Tailoring of mechanical properties of diisocyanate crosslinked gelatin-based hydrogels, Mater Res Soc Symp Proc, 2013, 1569, mrss13-1569-nn01-02.
  • T. Gebauer, A. T. Neffe, A. Lendlein, Influence of diisocyanate reactivity and water solubility on the formation and the mechanical properties of gelatin-based networks in water, Mater Res Soc Symp Proc, 2013, 1569, mrss13-1569-nn10-17.
  • C. Wischke, A. Krüger, T. Roch, B. F. Pierce, W. Li, F. Jung, A. Lendlein, Endothelial cell response to (co)polymer nanoparticles depending on the inflammatory environment and comonomer ratio, Europ J Pharm Biopharm, 2013, 84 (2), 288-296.
  • K. Trescher, T. Roch, K. Kratz, F. Jung, A. Lendlein, Test system for evaluating the influence of polymer properties on primary human keratinocytes and fibroblasts in mono- and coculture, J Biotech, 2013, 166, 58-64.
  • A. T. Neffe, M. von Ruesten-Lange, S. Braune, K. Luetzow, T. Roch, K. Richau, F. Jung, A. Lendlein, Poly(ethylene glycol) grafting to poly(ether imide) membranes: influence on protein adsorption and thrombocyte adhesion, Macromol Biosci, 2013, 13 (12), 1720-1728.
  • N. Welsch, Y. Lu, J. Dzubiella, M. Ballauff, Adsorption of proteins to functional nanoparticles, Polymer, 2013, 54 (12), 2835–2849.
  • D. Steinhilber, T. Rossow, S. Wedepohl, F. Paulus, S. Seiffert, and R. Haag, A microgel construction kit for bioorthogonal encapsulation and pH-controlled release of living cells, Angew Chem Int Edit, 2013, 52, 13538–13543; Ein Mikrogelbaukasten für die bioorthogonale Verkapselung und pH-gesteuerte Freisetzung von lebenden Zellen, Angew Chem, 2013, 125, 13780–13785.
  • D. Steinhilber, M. Witting, X. Zhang, M. Staegemann, F. Paulus, W. Friess, S. Küchler, R. Haag, Surfactant free preparation of biodegradable dendritic polyglycerol nanogels by inverse nanoprecipitation for encapsulation and release of pharmaceutical biomacromolecules, J Control Release, 2013, 169 (3), 289-295.
  • F. Di Lorenzo, S. Seiffert, Particulate and continuum mechanics of microgel pastes: effect and non-effect of compositional heterogeneity, Colloid Polym Sci, 2013, 291 (12), 2927–2933.
  • F. Di Lorenzo, S. Seiffert, Macro- and microrheology of heterogeneous microgel packings, Macromolecules, 2013, 46 (5), 1962–1972.
  • M. Sarem, F. Moztarzadeh, and M. Mozafari, How can genipin assist gelatin/carbohydrate chitosan scaffolds to act as replacements of load-bearing soft tissues? Carbohyd Polym, 2013, 93 (2), 635–643.
  • M. Sarem, F. Moztarzadeh, M. Mozafari, V. P. Shastri, Optimization strategies on the structural modeling of gelatin/chitosan scaffolds to mimic human meniscus tissue, Mater Sci Eng C, 2013, 33 (8), 4777-4785.
  • K. Krueger, C. Terne,C. Werner, U. Freudenberg, V. Jankowski, W. Zidek, J. Jankowski, Characterization of polymer membranes by MALDI mass spectrometric imaging techniques, Anal Chem, 2013, 85 (10), 4998−5004.
  • S. Heilmann, S. Küchler, C. Wischke, A. Lendlein, C. Stein, M. Schäfer-Korting, A thermosensitive morphine-containing hydrogel for the treatment of large-scale skin wounds, Int J Pharm, 2013, 444 (1–2), 96-102.

Publications 2012

  • A. T. Neffe, B. F. Pierce, J. Blaszkiewicz, A. Lendlein, Quantifying protein adsorption to physically crosslinked gelatin-based networks, Mater Res Soc Symp Proc, 2012, 1403, 145-150, mrsf11–1403–v05–04.
  • M. Lange, S. Braune, K. Luetzow, K. Richau, N. Scharnagl, M. Weinhart, A. T. Neffe, F. Jung, R. Haag, A. Lendlein, Surface functionalization of poly(ether imide) membranes with linear, methylated oligoglycerols for reducing thrombogenicity, Macromol Rapid Commun 2012, 33 (17), 1487–1492.
  • C. Yigit, N. Welsch, M. Ballauff, and J. Dzubiella, Protein Sorption to microgels: characterizing binding isotherms and driving forces, Langmuir, 2012, 28 (40), 14373-14385.
  • N. Welsch, J. Dzubiella, A. Graebert, and M. Ballauff, Protein binding to soft polymeric surfaces: a quantitative study by fluorescence spectroscopy, Soft Matter, 2012, 8, 12043.